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Multicenter iEEG Sleep Atlas
The Multicenter iEEG Sleep Atlas is an international collaboration collecting intracranial electroencephalography (EEG) recordings from patients with drug-resistant focal epilepsy implanted with stereo-EEG electrodes in addition to baseline clinical information, anatomical scans, and post-surgical assessment.
Included in the project are 24-hour and resting state recordings with sleep/wake annotations for sleep stage as well as all source codes used within this project. iEEG data is stored in BIDS standard format, optimized for re-use and data sharing, and can be visualized online in this project’s Electrophysiology Browser.
This project is a collaboration across 11 sites in 6 countries, targeting the understanding of region-specific differences in human sleep and generate knowledge on the distinct participation of various cortical regions in sleep. It aims to generate a unique dataset of 200 patients that will allow to study direct cortical recordings in the human brain as only possible in the context of pre-surgical epilepsy evaluation. Data collection is coordinated and harmonized across sites through this collaboration.
Contributors
Montreal Neurological Institute-Hospital, McGill University
- Dr. Jean Gotman
- Dr. Birgit Frauscher
- Dr. Nicolas von Ellenrieder
Centre hospitalier de l'Université de Montréal
- Dr. Dang Khoa Nguyen
Federation Hospitalo Universitaire NeuroPsyNov, Grenoble
- Dr. Philippe Kahane
Massachusetts General Hospital, Harvard University
- Dr. Vasileios Kokkinos
Mayo Clinic
- Dr. Gregory Worrell
University of Salzburg Christian Doppler-Kiinik
- Dr. Eugen Trinka
University Hospital Brno
- Dr. Milan Brazdil
Northwestern University
- Dr. Stephan Schuele
University of Bucharest
- Dr. Ioana Mindruta
University of Florida
- Dr. Giridhar Kalamangalam
Western University
- Dr. Suller Marti
This project is a continuation of the Open MNI iEEG Atlas project:
- Frauscher, B. et al., 2018. Atlas of the normal intracranial electroencephalogram: Neurophysiological awake activity in different cortical areas. Brain. https://doi.org/10.1093/brain/awy035
- Frauscher B, et al., 2018. High frequency oscillations in the normal human brain. Annals of Neurology. https://doi.org/10.1002/ana.25304
- von Ellenrieder N, et al., 2019. How the human brain sleeps: Direct cortical recordings from normal human sleep. Annals of Neurology. https://doi.org/10.1002/ana.25651
Funding
The multicenter MNI iEEG atlas is funded by CANARIE (RS3-050), NSERC (RGPIN-2020-04127, RGPIN-2020-00021), and supported by HBHL, CONP, and the MCIN (Alan Evans) group at the Montreal Neurological Institute-Hospital.
For more information about this collaboration, contact Dr. Birgit Frauscher at birgit.frauscher@mcgill.ca.
Related Projects
- Open MNI iEEG Atlas (2018-9)
- LORIS